2-Amino-4-methoxy-6-methyl-1,3,5-triazine → N-[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-4-nitrothiophene-2-sulfonamide

HRID 236534

Reaktionsgleichung

Reaktionsgleichung von HRID 236534
[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[N:5]=[C:4]([CH3:10])[N:3]=1.[N+:11]([C:14]1[CH:15]=[C:16]([S:19]([N:22]=[C:23]=[O:24])(=[O:21])=[O:20])[S:17][CH:18]=1)([O-:13])=[O:12]>C(#N)C>[CH3:9][O:8][C:6]1[N:5]=[C:4]([CH3:10])[N:3]=[C:2]([NH:1][C:23]([NH:22][S:19]([C:16]2[S:17][CH:18]=[C:14]([N+:11]([O-:13])=[O:12])[CH:15]=2)(=[O:21])=[O:20])=[O:24])[N:7]=1

Komponenten

4

Edukt 2

HCID 154662-Amino-4-methoxy-6-methyl-1,3,5-triazineHCID 202157024-Nitrothiophene-2-sulfonyl isocyanate

Produkt 1

HCID 13472988N-[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-4-nitrothiophene-2-sulfonamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

To 1.4 g of 2-amino-4-methoxy-6-methyl-1,3,5-triazine suspended in 25 ml of anhydrous acetonitrile with stirring at ambient temperature was added 2.4 g of 4-nitrothiophene-2-sulfonyl isocyanate. After stirring for sixteen hours at ambient temperature, the product which was present as a precipitate was removed by filtration and washed with 1-chlorobutane. It melted at 188° with decomposition and showed infrared absorption spectrum peaks at 1740, 1600 and 1560 cm-1 consistent for the desired aminocarbonylsulfonamide structure.

Aufarbeitung

  1. stirringAfter stirring for sixteen hours at ambient temperature
  2. customwas removed by filtration
  3. washwashed with 1-chlorobutane
  4. customabsorption spectrum peaks at 1740, 1600 and 1560 cm-1 consistent for the desired aminocarbonylsulfonamide structure

Quellen und Nachweise

ORD-Eintrag
ord-a885e71857244ac1afb803c6848aafc2
Quelldatensatz
uspto-grants-1987_02
Patentnummer
US04645529

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