1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methyl-3-(2,2,2-trifluoroethoxymethyl)piperidine → (S)-1-[(S)-1-(2,3-Dihydrobenzo[1,4]dioxin-2-yl)methyl]-3-methyl-3-(2,2,2-trifluoroethoxymethyl)piperidine
Reaktionsgleichung
O1C2C=CC=CC=2OC[C@@H]1CN1CCC[C@@](CO)(C)C1.[O:21]1[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[O:24][CH2:23][CH:22]1[CH2:31][N:32]1[CH2:37][CH2:36][CH2:35][C:34]([CH3:45])([CH2:38][O:39][CH2:40][C:41]([F:44])([F:43])[F:42])[CH2:33]1>>[O:21]1[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[O:24][CH2:23][C@@H:22]1[CH2:31][N:32]1[CH2:37][CH2:36][CH2:35][C@:34]([CH3:45])([CH2:38][O:39][CH2:40][C:41]([F:43])([F:42])[F:44])[CH2:33]1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
Prepared from {(S)-1-[(S)-1-(2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]-3-methylpiperidin-3-yl}methanol as described for 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methyl-3-(2,2,2-trifluoroethoxymethyl)piperidine.