3,4-Dimethoxybenzeneacetonitrile → HCID 11965579, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[N:3]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[S:5][C:6]=1[CH:7]=O.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][C:25]=1[O:26][CH3:27])[CH2:20][C:21]#[N:22]>>[CH3:15][O:16][C:17]1[CH:18]=[C:19](/[C:20](=[CH:7]/[C:6]2[S:5][C:4]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)=[N:3][C:2]=2[CH3:1])/[C:21]#[N:22])[CH:23]=[CH:24][C:25]=1[O:26][CH3:27]Komponenten
3
Versuchsvorschrift
4-Methyl-2-phenyl-1,3-thiazole-5-carbaldehyde (407 mg) was condensed with 3,4-dimethoxybenzyl cyanide (354 mg) through Method A (production step 2), to thereby yield the target product (yield: 667 mg, 92%).
Quellen und Nachweise
- ORD-Eintrag
- ord-b54839898edf4b4f9c49b58b44c1fe84
- Quelldatensatz
- uspto-grants-2014_04