N,N-dipropylsulfamoyl chloride → 1-[(Dipropylamino)sulfonyl]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]-piperazine
Reaktionsgleichung
[CH2:1]([N:4]([CH2:9][CH2:10][CH3:11])[S:5](Cl)(=[O:7])=[O:6])[CH2:2][CH3:3].[Cl:12][C:13]1[CH:22]=[C:21]2[C:16]([C:17]([NH:23][C:24]3[CH:29]=[CH:28][C:27]([S:30]([N:33]4[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]4)(=[O:32])=[O:31])=[CH:26][CH:25]=3)=[CH:18][CH:19]=[N:20]2)=[CH:15][CH:14]=1>>[CH2:1]([N:4]([CH2:9][CH2:10][CH3:11])[S:5]([N:36]1[CH2:37][CH2:38][N:33]([S:30]([C:27]2[CH:28]=[CH:29][C:24]([NH:23][C:17]3[C:16]4[C:21](=[CH:22][C:13]([Cl:12])=[CH:14][CH:15]=4)[N:20]=[CH:19][CH:18]=3)=[CH:25][CH:26]=2)(=[O:31])=[O:32])[CH2:34][CH2:35]1)(=[O:7])=[O:6])[CH2:2][CH3:3]Komponenten
3
Versuchsvorschrift
In the manner given in Example 13 but using dipropylsulfamoyl chloride in place of dimethylsulfamoyl chloride and [[4-[[7-chloro-4-quinolinyl]-amino]phenyl]sulfonyl]piperazine in place of [[4-[(7-trifluoromethyl-4-quinolinyl)amino]phenyl]-sulfonyl]piperazine, 1-[(dipropylamino)sulfonyl]-4-[[4-[[7-chloro-4-quinolinyl]amino]phenyl]sulfonyl]-piperazine is obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-21f970de35b84ede925d7f2967ef573b