5-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine → 7-(o-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]-1,2,4-triazine

HRID 237093Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 237093
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH:14][NH2:15])[N:11]=[N:12][CH:13]=1.[C:16]([O-])([O-])(OCC)[CH3:17]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[N:12][N:11]2[C:16]([CH3:17])=[N:15][N:14]=[C:10]2[N:9]=1

Komponenten

3

Edukt 2

HCID 125812735-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazineHCID 86598186Ethyl ortho-acetate

Produkt 1

HCID 125812757-(o-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]-1,2,4-triazine

Versuchsvorschrift

A mixture of 6.15 g. of 5-(o-fluorophenyl)-3-hydrazino-1,2,4-triazine and 50 ml. of ethyl orthoacetate is refluxed for 2.5 hours, cooled and the solid is collected by filtration and washed with hexane and ethanol, giving the desired product as yellow crystals, m.p. 227°-229° C.

Aufarbeitung

  1. additionA mixture of 6.15 g
  2. temperaturecooled
  3. filtrationthe solid is collected by filtration
  4. washwashed with hexane and ethanol

Quellen und Nachweise

ORD-Eintrag
ord-8993d7c1ae9a4ce490a33fcb8a92ee1c
Quelldatensatz
uspto-grants-1979_06
Patentnummer
US04159375

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