diethyl 3,4-dihydro-7-[3-(4-chlorophenoxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoate → 3,4-dihydro-7-[3-(2-naphthalenyloxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoic acid
Reaktionsgleichung
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:40]=[CH:39][C:19]2[C:20](=[O:38])[CH2:21][C:22]([CH2:31][CH2:32][C:33]([O:35]CC)=[O:34])([CH2:24][CH2:25][C:26]([O:28]CC)=[O:27])[O:23][C:18]=2[C:17]=1[CH2:41][CH2:42][CH3:43].ClC1C=CC(OCCCOC2C=CC3C(=O)CC(CCC(OCC)=O)(CCC(OCC)=O)OC=3C=2CCC)=CC=1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:40]=[CH:39][C:19]2[C:20](=[O:38])[CH2:21][C:22]([CH2:31][CH2:32][C:33]([OH:35])=[O:34])([CH2:24][CH2:25][C:26]([OH:28])=[O:27])[O:23][C:18]=2[C:17]=1[CH2:41][CH2:42][CH3:43]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared by the method of Example 22 substituting 539 mg of the title product of Example 23 for the title product of Example 21. Crystallization from 5:1 ethyl acetate:hexane yielded 303 mg, m.p. 157.5°-158° C.