diethyl 3,4-dihydro-7-[3-(4-chlorophenoxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoate → 3,4-dihydro-7-[3-(2-propylphenoxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoic acid
Reaktionsgleichung
[CH2:1]([C:4]1[CH:42]=[CH:41][CH:40]=[CH:39][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:35]=[CH:34][C:14]2[C:15](=[O:33])[CH2:16][C:17]([CH2:26][CH2:27][C:28]([O:30]CC)=[O:29])([CH2:19][CH2:20][C:21]([O:23]CC)=[O:22])[O:18][C:13]=2[C:12]=1[CH2:36][CH2:37][CH3:38])[CH2:2][CH3:3].ClC1C=CC(OCCCOC2C=CC3C(=O)CC(CCC(OCC)=O)(CCC(OCC)=O)OC=3C=2CCC)=CC=1>>[CH2:1]([C:4]1[CH:42]=[CH:41][CH:40]=[CH:39][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:35]=[CH:34][C:14]2[C:15](=[O:33])[CH2:16][C:17]([CH2:26][CH2:27][C:28]([OH:30])=[O:29])([CH2:19][CH2:20][C:21]([OH:23])=[O:22])[O:18][C:13]=2[C:12]=1[CH2:36][CH2:37][CH3:38])[CH2:2][CH3:3]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared by the method of Example 22 substituting the title product of Example 40 (446 mg) for the title product of Example 21. Crystallization from ethyl acetate/hexane produced 252 mg as a solid, m.p. 163°-165° C.