1-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazine → [4-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(5-methanesulfonyl-2-thiazol-2-yl-phenyl)-methanone
Reaktionsgleichung
[F:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[CH3:18][S:19]([C:22]1[CH:23]=[CH:24][C:25]([C:31]2[S:32][CH:33]=[CH:34][N:35]=2)=[C:26]([CH:30]=1)[C:27](O)=[O:28])(=[O:21])=[O:20]>>[F:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][N:15]([C:27]([C:26]3[CH:30]=[C:22]([S:19]([CH3:18])(=[O:21])=[O:20])[CH:23]=[CH:24][C:25]=3[C:31]3[S:32][CH:33]=[CH:34][N:35]=3)=[O:28])[CH2:14][CH2:13]2)[CH:5]=[CH:6][C:7]=1[C:8]([F:9])([F:11])[F:10]Komponenten
3
Versuchsvorschrift
The title compound was prepared according to the procedure E described for Example 9 from 1-(3-Fluoro-4-trifluoromethyl-phenyl)-piperazine (Example P) and 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid (Example O). MS (ISP): 514.5 MH+.
Quellen und Nachweise
- ORD-Eintrag
- ord-9f39c51a17d74ea8bad392506862a3bc