N-bromobutanimide → HCID 178448705, Verbindung
Reaktionsgleichung
[CH2:1]([N:5]1[C:13]2[NH:12][CH:11]=[N:10][C:9]=2[C:8]2=[N:14][N:15]=[CH:16][N:7]2[C:6]1=[O:17])[CH:2]([CH3:4])[CH3:3].[Br:18]N1C(=O)CCC1=O>C1COCC1>[Br:18][C:11]1[NH:12][C:13]2[N:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[C:6](=[O:17])[N:7]3[CH:16]=[N:15][N:14]=[C:8]3[C:9]=2[N:10]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 6-isobutyl-6,7-dihydro-5H-[1,2,4]triazolo[3,4-i]purin-5-one (9.4 mg, 40 mmol) in THF (5 ml) was added N-bromosuccinimide (8 mg, 44.7 mmol). The mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated, and the residue was purified by preparative LCMS (method A) to provide the desired product. LCMS calculated for C10H12BrN6O (M+H): 311.0; found 310.9, 313.0.