3,4-Dimethoxyaniline → N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3,4-Dimethoxyaniline	HCID 22770	—
Edukt	5-Methyl-2-(methylthio)-7-phenylimidazo[5,1-F][1,2,4]triazine	HCID 53471832	—
Edukt	5-Methyl-2-(methylsulfonyl)-7-phenylimidazo[5,1-F][1,2,4]triazine	HCID 53471833	—
Lösungsmittel	Ethanol	HCID 702	—
Produkt	N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine	HCID 11405758	36,6%

Reaktionsschritte

Applying the displacement procedure, using 5-methyl-2-(methylthio)-7-phenylimidazo[5,1-f][1,2,4]triazine (Intermediate 72) (50 mg, 0.17 mmol), 3,4-dimethoxyaniline (26.5 mg, 0.17 mmol) and ethanol (2.5 mL) to afford N-[3,4-bis(methyloxy)phenyl]-5-methyl-7-phenylimidazo[5,1-f][1,2,4]triazin-2-amine (22.5 mg) as a yellow solid. MS m/z 362 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07462614B2
Quelldatensatz	uspto-grants-2008_12
ORD ID	ord-e5c039399f834a8f8316774027d03abc
Quellennotiz	uspto-grants-2008_12