4-Bromo-3,5-dimethylphenol → 4-((4-Bromo-3,5-dimethylphenoxy)methyl)tetrahydro-2H-pyran-4-ol
Reaktionsgleichung
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([OH:9])=[CH:4][C:3]=1[CH3:10].[O:11]1[C:13]2([CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)[CH2:12]1>>[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([O:9][CH2:12][C:13]2([OH:11])[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:4][C:3]=1[CH3:10]Komponenten
3
Versuchsvorschrift
The title compound is prepared from 4-bromo-3,5-dimethylphenol and 1,6-dioxaspiro[2.5]octane following a procedure analogous to that described in Step 3 of Intermediate 2. LC (method 7): tR=1.04 min; Mass spectrum (ESI−): m/z=313 [M−H]−.
Quellen und Nachweise
- ORD-Eintrag
- ord-3522e7585b5d4f6396a760adec6c2281
- Quelldatensatz
- uspto-grants-2014_02
- Patentnummer
- US08642585B2
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