HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromobenzenesulfonyl chloride → N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-bromobenzenesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Bromobenzenesulfonyl chloride | HCID 520403 | — |
| Edukt | 3-Methoxy-5-methyl-2-pyrazinamine | HCID 10701894 | — |
| Produkt | N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-bromobenzenesulfonamide | HCID 22574647 | — |
Reaktionsschritte
2-amino-3-methoxy-5-methylpyrazine (1.50 g, 10.8 mmol; synthesized according to Bradbury, R. H., et. al. J. Med. Chem. 1997, 40, 996-1004) and 2-bromobenzenesulfonyl chloride (2.80 g, 11.0 mmol) were reacted according to the procedure of Example 25, Step A. 44A was a pink solid, 2.0 g (52%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06852745B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-32684a7f2dc54df6a229f66d61bb8a06 |
| Quellennotiz | uspto-grants-2005_02 |