2-Bromo-5-methylpyrazine → 2-(4-Bromo-3,5-dimethyl-phenyl)-5-methyl-pyrazine

HRID 237632Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 237632
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][C:3]=1[CH3:18].Br[C:20]1[CH:25]=[N:24][C:23]([CH3:26])=[CH:22][N:21]=1>>[Br:1][C:2]1[C:3]([CH3:18])=[CH:4][C:5]([C:20]2[CH:25]=[N:24][C:23]([CH3:26])=[CH:22][N:21]=2)=[CH:6][C:7]=1[CH3:8]

Komponenten

3

Edukt 2

HCID 224193462-Bromo-5-methylpyrazineHCID 569731362-(4-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Produkt 1

HCID 866973052-(4-Bromo-3,5-dimethyl-phenyl)-5-methyl-pyrazine

Versuchsvorschrift

The title compound is prepared from 2-bromo-1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzene and 2-bromo-5-methyl-pyrazine following a procedure analogous to that described in Step 1 of Intermediate 56. Mass spectrum (ESI+): m/z=277/279 (Br) [M+H]+.

Quellen und Nachweise

ORD-Eintrag
ord-4e38529afd4944a79d4748780932dc59
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08642585B2

Notizen zur Reaktion

Wird geladen…