HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Propynoic acid, 3-phenyl-, ethyl ester → (S)-2-(4-Cyclohexyl-phenoxymethyl)-5-phenyl-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Propynoic acid, 3-phenyl-, ethyl ester | HCID 91516 | — |
| Edukt | (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine | HCID 66875140 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | (S)-2-(4-Cyclohexyl-phenoxymethyl)-5-phenyl-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-one | HCID 59252505 | — |
Reaktionsschritte
The title compound was prepared from (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine and ethyl phenylpropiolate employing the procedure described in Example 76. [α]D25 +100.26 (c 0.507, DMSO).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08642603B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-7047615d5b934326a83259fe56822e95 |
| Quellennotiz | uspto-grants-2014_02 |