Methyl iodide → 1-methyl-2-(methylsulfanyl)-4,5-dihydro-1H-imidazole hydroiodide

HRID 237929Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 237929
[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[S:7].[CH3:8][I:9]>CC(C)=O>[IH:9].[CH3:1][N:2]1[CH2:6][CH2:5][N:4]=[C:3]1[S:7][CH3:8]

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 2733224Methylethylenethiourea

Produkt 1

HCID 122815051-methyl-2-(methylsulfanyl)-4,5-dihydro-1H-imidazole hydroiodideAusbeute 77 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a suspension of 1-methylimidazolidine-2-thione (5.17 g, 44.5 mmol) in acetone (50 mL) was added MeI (2.9 mL, 46.6 mmol). The solution was allowed to stir at room temperature for 4 h and the resulting solid was quickly filtered and then dried in vacuo to give 1-methyl-2-(methylthio)-4,5-dihydro-1H-imidazole hydroiodide (8.79 g, 77%) as beige solid.

Aufarbeitung

  1. filtrationthe resulting solid was quickly filtered
  2. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-fdb60214d5144257b439b350e79df1cf
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08642025B2

Notizen zur Reaktion

Wird geladen…