HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chlorophenylglyoxylic acid → 2-(4-chlorophenyl)-4-cyclopropylmethylpyrido[2,3-b]pyrazin-3(4H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chlorophenylglyoxylic acid | HCID 145998 | — |
| Edukt | N2-(cyclopropylmethyl)pyridine-2,3-diamine | HCID 28902457 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 2-(4-chlorophenyl)-4-cyclopropylmethylpyrido[2,3-b]pyrazin-3(4H)-one | HCID 44218437 | — |
Reaktionsschritte
430 mg (2.63 mM) of N2-(cyclopropylmethyl)pyridine-2,3-diamine and 485.4 mg (2.63 mM) of (4-chlorophenyl)(oxo)acetic acid in 6 ml of methanol were refluxed for 16 h. A solid crystallized. The compound was filtered and washed with methanol to give
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08642617B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-f13aca96aa2344e19f3ce41471f785d1 |
| Quellennotiz | uspto-grants-2014_02 |