HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trimethylsilylacetylene → 5-Trimethylsilanylethynyl-1H-indazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trimethylsilylacetylene | HCID 66111 | — |
| Edukt | 5-Iodo-1H-indazole | HCID 21894739 | — |
| Produkt | 5-Trimethylsilanylethynyl-1H-indazole | HCID 57950741 | 46% |
Reaktionsschritte
In an adaption of GP 8a, 5-Iodo-1H-indazole (0.98 g, 4.02 mmol) was reacted with trimethylsilyl acetylene (0.60 mL, 4.22 mmol) at 90° C. for 5 h to give 395 mg (46%) of pure 5-(trimethylsilyl)ethynyl-1H-indazole.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08642611B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-d97e33d95d5b435aabfb6172bc657155 |
| Quellennotiz | uspto-grants-2014_02 |