Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Water | HCID 962 | — |
| Edukt | 4-(Bromomethyl)benzenesulfonyl chloride | HCID 2734409 | — |
| Edukt | Methylamine hydrochloride | HCID 6364545 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-(Bromomethyl)-N-methylbenzenesulfonamide | HCID 10015645 | — |
Reaktionsschritte
To a chilled (0° C.) stirred solution of 4-(bromomethyl)-benzenesulfonylchloride (3.0 g, 11 mmol) in DCM (100 mL) was added methylamine hydrochloride (1.2 g, 12 mmol). After 30 minutes, water (100 mL) was added. The organic layer was separated, washed with brine (30 mL), and dried over sodium sulfate and concentrated in vauco to afford 4-bromomethyl-N-methyl-benzenesulfonamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08263597B2 |
|---|
| Quelldatensatz | uspto-grants-2012_09 |
|---|
| ORD ID | ord-4b9410be52a34c02a5e9b936ebade2bb |
|---|
| Quellennotiz | uspto-grants-2012_09 |
|---|
