HCID 67309189, Verbindung → HCID 15539217, Verbindung

HRID 2383335Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2383335
Br[C:2]1[C:3]([CH3:16])=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=[C:7]2[OH:15]>C(O)C.[C].[Pd]>[OH:15][C:7]1[C:6]2[C:11](=[CH:2][C:3]([CH3:16])=[CH:4][CH:5]=2)[CH:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=1

Komponenten

4

Edukt 1

HCID 67309189HCID 67309189, Verbindung

Produkt 1

HCID 15539217HCID 15539217, VerbindungAusbeute 98,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 8-bromo-4-hydroxy-7-methylnaphthalene-2-carboxylic acid (0.45 g) in ethanol (8 mL) was added palladium-carbon (180 mg) in 3 parts, and the mixture was stirred at room temperature for 2 days under a hydrogen atmosphere. The insoluble material was removed by filtering through a Celite pad, and the filtrate was concentrated to give the title compound (0.32 g).

Aufarbeitung

  1. customThe insoluble material was removed
  2. filtrationby filtering through a Celite pad
  3. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-8a76776f05be4de3989f4d05de0a35ab
Quelldatensatz
uspto-grants-2012_09
Patentnummer
US08263622B2

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