Hydrochloric Acid → HCID 53904370, Verbindung

HRID 2384068Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2384068
C([O:3][C:4](=[O:13])[CH2:5][C:6]1[S:7][C:8]([CH2:11][CH3:12])=[N:9][N:10]=1)C.[OH-].[Na+].Cl>C(O)C>[CH2:11]([C:8]1[S:7][C:6]([CH2:5][C:4]([OH:13])=[O:3])=[N:10][N:9]=1)[CH3:12]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 67505705(5-Ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid ethyl ester

Produkt 1

HCID 53904370HCID 53904370, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Next, to a solution of (5-ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid ethyl ester (230 mg, 1.15 mmol) in ethanol (5 mL) is added aqueous 1M NaOH (2 mL, 2.0 mmol) and the mixture is stirred at room temperature for 18 hours. The mixture is acidified with aqueous 1M HCl and the ethanol is removed under reduced pressure. The remaining aqueous solution is lyophilized to give (5-ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid.

Aufarbeitung

  1. customthe ethanol is removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-4d612c813040417f91833d76880ca0f6
Quelldatensatz
uspto-grants-2012_09
Patentnummer
US08263629B2

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