5-Bromosalicylic acid → HCID 86595540, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][O:13][C:14](=[O:28])[CH2:15][C:16]1[S:20][C:19]([NH2:21])=[N:18][C:17]=1[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH3:12][O:13][C:14](=[O:28])[CH2:15][C:16]1[S:20][C:19]([NH:21][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([Br:1])[CH:3]=[CH:4][C:5]=2[OH:11])=[N:18][C:17]=1[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1Komponenten
3
Versuchsvorschrift
Using 5-bromosalicylic acid and 2-amino-4-phenylthiazole-5-acetic acid methyl ester as the raw materials, the same operation as the example 195(3) gave the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-cca918f8bf7d4df6aad041060675ca51
- Quelldatensatz
- uspto-grants-2012_09
- Patentnummer
- US08263657B2