Methyl iodide → 5-[1-(4-Methanesulfonyl-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one
Reaktionsgleichung
[CH3:1][S:2]([C:5]1[CH:28]=[CH:27][C:8]([CH2:9][N:10]2[C:18]3[C:13](=[CH:14][C:15]([CH:19]=[C:20]4[S:24][C:23](=[S:25])[NH:22][C:21]4=[O:26])=[CH:16][CH:17]=3)[CH:12]=[N:11]2)=[C:7]([C:29]([F:32])([F:31])[F:30])[CH:6]=1)(=[O:4])=[O:3].[CH3:33]I>>[CH3:1][S:2]([C:5]1[CH:28]=[CH:27][C:8]([CH2:9][N:10]2[C:18]3[C:13](=[CH:14][C:15]([CH:19]=[C:20]4[S:24][C:23]([S:25][CH3:33])=[N:22][C:21]4=[O:26])=[CH:16][CH:17]=3)[CH:12]=[N:11]2)=[C:7]([C:29]([F:32])([F:31])[F:30])[CH:6]=1)(=[O:4])=[O:3]Komponenten
3
Versuchsvorschrift
5-[1-(4-Methanesulfonyl-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one was prepared from 5-[1-(4-Methanesulfonyl-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-one and methyl iodide following General Procedure C.
Quellen und Nachweise
- ORD-Eintrag