1-(2,2-Difluoroethyl)piperazine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(2,2-Difluoroethyl)piperazine	HCID 19622797	—
Edukt	5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one	HCID 67240123	—
Produkt	5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-one	HCID 76756286	—

Reaktionsschritte

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 1-(2,2-difluoro-ethyl)piperazine following General Procedure C.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08263781B2
Quelldatensatz	uspto-grants-2012_09
ORD ID	ord-b1a11522c3ef40e1a741d07a54e5ff4d
Quellennotiz	uspto-grants-2012_09