Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ammonium Chloride | HCID 25517 | — |
| Edukt | 4-(4-Nitrobenzyl)morpholine | HCID 783183 | — |
| Katalysator | Iron | HCID 23925 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 4-(Morpholinomethyl)aniline | HCID 776851 | — |
Reaktionsschritte
A mixture of 4-[(4-nitrophenyl)methyl]morpholine (220 mg, 1.0 mmol, Step A), iron powder (279 mg, 5.0 mmol) and NH4Cl (39 mg, 0.7 mmol) in EtOH (3 mL) and H2O (3 mL) was stirred for 4 h at 80° C. Filtration and concentration gave the crude 4-(morpholin-4-ylmethyl)-phenylamine, which was used in next step without further purification.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08642624B2 |
|---|
| Quelldatensatz | uspto-grants-2014_02 |
|---|
| ORD ID | ord-22b5b04e01b946c987ac29d8bc2a960d |
|---|
| Quellennotiz | uspto-grants-2014_02 |
|---|
