HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Amino-1-Boc-piperidine → 4-[5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| Edukt | 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde | HCID 24901981 | — |
| Produkt | 4-[5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 86603293 | — |
Reaktionsschritte
Intermediate 89 was coupled with 4-Amino-piperidine-1-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product was >95% pure and had the expected M+H+ of 421.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08268822B2 |
| Quelldatensatz | uspto-grants-2012_09 |
| ORD ID | ord-b45e670e9a9147ca9e6b8859f356cb87 |
| Quellennotiz | uspto-grants-2012_09 |