2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acid → 3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acid	HCID 44119554	—
Edukt	3-Amino-6-(3,4-dichloro-phenyl)-pyrazine-2-carboxylic acid methoxy-methyl amide	HCID 86634542	—
Produkt	3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amide	HCID 86634543	—

Reaktionsschritte

This compound is prepared in an analogous manner to intermediate B substituting 3,4 dichlorophenyl boronic acid with 2-methyl-5-(N-morpholinylsulfonyl) phenyl boronic acid in step 2. The title compound is obtained as an off-white solid. [M+H]+ 422.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08268834B2
Quelldatensatz	uspto-grants-2012_09
ORD ID	ord-d102bace775e4209b0eab820f6a1c22b
Quellennotiz	uspto-grants-2012_09