1-Isopropenyl-4-(methylsulfonyl)-2-nitrobenzene → 2-Isopropenyl-5-(methylsulfonyl)aniline

HRID 2390175Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2390175
CS(C1C=CC(/C=C/C)=C(C=1)N)(=O)=O.[C:15]([C:18]1[CH:23]=[CH:22][C:21]([S:24]([CH3:27])(=[O:26])=[O:25])=[CH:20][C:19]=1[N+:28]([O-])=O)([CH3:17])=[CH2:16]>>[C:15]([C:18]1[CH:23]=[CH:22][C:21]([S:24]([CH3:27])(=[O:25])=[O:26])=[CH:20][C:19]=1[NH2:28])([CH3:17])=[CH2:16]

Komponenten

3

Edukt 2

HCID 585218981-Isopropenyl-4-(methylsulfonyl)-2-nitrobenzene2×HCID 585220135-(methylsulfonyl)-2-[(1E)-prop-1-en-1-yl]aniline

Produkt 1

HCID 585219612-Isopropenyl-5-(methylsulfonyl)aniline

Versuchsvorschrift

Following the general method as outlined in Intermediate 60, starting from 1-isopropenyl-4-(methylsulfonyl)-2-nitrobenzene (Intermediate 88), the title compound was obtained as an orange solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.

Quellen und Nachweise

ORD-Eintrag
ord-00bb0b92201f457db68e0d6db14409a9
Quelldatensatz
uspto-grants-2012_09
Patentnummer
US08273769B2

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