2,3-Epoxypropyl 4'-methoxyphenyl ether → Phenyl glycidyl ether

HRID 239019

Reaktionsgleichung

Reaktionsgleichung von HRID 239019
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][NH:8][C:9]([N:11]2[C:15]3C=CC=[CH:19][C:14]=3[N:13](C)[C:12]2=[O:21])=[O:10])[CH2:3][CH2:2]1.CO[C:24]1[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH:32]2[O:34][CH2:33]2)=[CH:26][CH:25]=1>>[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][NH:8][C:9]([N:11]2[C:29]3[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=3[N:13]([CH:14]([CH3:15])[CH3:19])[C:12]2=[O:21])=[O:10])[CH2:3][CH2:2]1.[O:34]1[CH:32]([CH2:31][O:30][C:27]2[CH:26]=[CH:25][CH:24]=[CH:29][CH:28]=2)[CH2:33]1

Komponenten

4

Edukt 2

HCID 166462,3-Epoxypropyl 4'-methoxyphenyl etherHCID 673782053-Methyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide

Produkt 2

HCID 31217Phenyl glycidyl etherHCID 442491883-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide

Versuchsvorschrift

The procedure given in Example 104 was followed using 3-methyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and glycidyl 4-methoxyphenyl ether as a reactant, instead of 3-isopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 1,2-epoxy-3-phenoxypropane, to give the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-20f44c5fbb9747ca8b66a6cc25461905
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08642772B2

Verknüpfte Notizen

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