HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-4'-fluoropropiophenone → 3-Chloropropiophenone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-4'-fluoropropiophenone | HCID 67672 | — |
| Edukt | 3-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide | HCID 44249188 | — |
| Produkt | 3-Chloropropiophenone | HCID 70295 | — |
| Produkt | 3-Cyclopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide | HCID 67369254 | — |
Reaktionsschritte
The procedure given in Example 135 was followed using 3-isopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 3-chloro-4′-fluoropropiophenone as a reactant, instead of 3-cyclopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 3-chloropropiophenone, to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08642772B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-28e9a5a562df48688c3b31079b5d94b8 |
| Quellennotiz | uspto-grants-2014_02 |