Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → HCID 56594781, Verbindung
Reaktionsgleichung
C([O:5][C:6](=[O:18])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[C:16]#[CH:17])(C)(C)C.Br[C:20]1[CH:21]=[C:22]([S:27]([CH2:30][CH2:31][CH2:32][OH:33])(=[O:29])=[O:28])[CH:23]=[CH:24][C:25]=1[CH3:26]>>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:5])=[O:18])=[C:10]([C:16]#[C:17][C:20]2[CH:21]=[C:22]([S:27]([CH2:30][CH2:31][CH2:32][OH:33])(=[O:29])=[O:28])[CH:23]=[CH:24][C:25]=2[CH3:26])[CH:11]=1Komponenten
3
Versuchsvorschrift
Following the general method as outlined in Example 37, starting from tert-butyl(4-chloro-2-ethynyl phenoxy)acetate (Intermediate 3) and 3-[(3-bromo-4-methylphenyl)sulfonyl]propan-1-ol (Intermediate 68), the title compound was obtained as a yellow solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-f45ca1d76f2f45b5ab31318ec8d08a7a
- Quelldatensatz
- uspto-grants-2012_09