Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | Benzoic acid, 3,5-dibromo- | HCID 12063 | — |
| Edukt | HCID 178418348 | HCID 178418348 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | 1-(3,5-Dibromophenyl)ethanone | HCID 621825 | — |
Reaktionsschritte
To a solution of 3,5-dibromobenzoic acid (2.5 g, 8.9 mmol) in Et2O (30 mL) at 0° C. was added methyllithium (1.6M in Et2O; 12.3 mL, 19.6 mmol) dropwise. The reaction was stirred at 0° C. for 2 hours, and then worked-up with EtOAc and 10% aqueous HCl. The crude material was purified by silica gel chromatography to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08273780B2 |
|---|
| Quelldatensatz | uspto-grants-2012_09 |
|---|
| ORD ID | ord-478e695e1dad4f818306169e89307e2c |
|---|
| Quellennotiz | uspto-grants-2012_09 |
|---|
