1,4-Dioxane hydrochloride → 4-[5-(Propan-2-YL)-1,3,4-oxadiazol-2-YL]piperidine

Beteiligte Stoffe

Reaktionsschritte

100 mL saturated dioxane-HCl was added to 16 g 4-(5-isopropyl-(1,3,4) oxadiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester in 100 mL dioxane at 0° C. The mixture was stirred at RT for 2 h. The precipitate was filtered and washed with ethyl acetate to give 12.3 g of the desired product.

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