2-(2-Phenylethyl)oxirane → 1-Amino-4-phenylbutan-2-ol

HRID 2391944

Reaktionsgleichung

Reaktionsgleichung von HRID 2391944
[C:1]1([CH2:7][CH2:8][CH:9]2[CH2:11][O:10]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH3:12].CO>>[NH2:12][CH2:11][CH:9]([OH:10])[CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

3

Edukt 2

HCID 1359552-(2-Phenylethyl)oxiraneHCID 21705897Ammonia methanol

Produkt 1

HCID 157609871-Amino-4-phenylbutan-2-ol

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

2-(2-phenylethyl)oxirane (8.0 g, 54 mmol) was placed in a sealed tube with 7N NH3-MeOH (130 mL) and stirred 2 hours at 70° C. followed by concentration to a clear oil (and was used without further purification in the following step.

Aufarbeitung

  1. concentrationfollowed by concentration to a clear oil (and
  2. customwas used without further purification in the following step

Quellen und Nachweise

ORD-Eintrag
ord-2fafa5b6418f48e9972a2ce2156309a0
Quelldatensatz
uspto-grants-2012_09
Patentnummer
US08273782B2

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