HCID 18979130, Verbindung → HCID 18979236, Verbindung

HRID 2393180Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2393180
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([O:20]COC)=O.[NH2:24][OH:25].CO>[Cl-].[NH4+]>[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([NH:24][OH:25])=[O:20]

Komponenten

4

Edukt 2

HCID 18979130HCID 18979130, VerbindungHCID 86645014HCID 86645014, Verbindung

Produkt 1

HCID 18979236HCID 18979236, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 25517Ammonium ChlorideLösungsmittel

Versuchsvorschrift

The methoxymethyl 7-(1-amino-2-naphthyl)heptanoate (0.3 g) was added to 1M hydroxylamine/methanol (2.85 ml) and the mixture was stirred at room temperature for 1.5 hours. This reaction mixture was poured in saturated aqueous ammonium chloride solution and extracted with ethyl acetate. The organic layer was washed with water, dried, and concentrated to dryness, and the residue was recrystallized from hexane-ether to provide the title compound (0.116 g).

Aufarbeitung

  1. extractionextracted with ethyl acetate
  2. washThe organic layer was washed with water
  3. customdried
  4. concentrationconcentrated to dryness
  5. customthe residue was recrystallized from hexane-ether

Quellen und Nachweise

ORD-Eintrag
ord-9b0415ea17bb4a90b9bd1176d9006b47
Quelldatensatz
uspto-grants-1998_09
Patentnummer
US05804601

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