HCID 9798400, Verbindung → HCID 18977165, Verbindung

HRID 2393749Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2393749
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1.[ClH:27].C(O)C>C(O)C>[ClH:27].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1

Komponenten

4

Edukt 2

HCID 9798400HCID 9798400, VerbindungHCID 21887872Ethanol hydrochloride

Produkt 1

HCID 18977165HCID 18977165, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

In hot ethanol (180 ml) was dissolved 8.9 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one. A 18% hydrochloric acid-ethanol solution (10 ml) was added to the solution, and the mixture was left to stand at room temperature. Precipitated crystal was collected by filtration and washed with cold ethanol to obtain 9.3 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one hydrochloride.

Aufarbeitung

  1. waitthe mixture was left
  2. customto stand at room temperature
  3. customPrecipitated crystal
  4. filtrationwas collected by filtration
  5. washwashed with cold ethanol

Quellen und Nachweise

ORD-Eintrag
ord-5863711c96ab4d5488285f496ae817ee
Quelldatensatz
uspto-grants-1998_09
Patentnummer
US05808065

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