1-(2,6-Dimethylpyridin-4-yl)ethan-1-one → HCID 54681250, Verbindung
Reaktionsgleichung
[C:1]([C:4]1[CH:9]=[C:8]([CH3:10])[N:7]=[C:6]([CH3:11])[CH:5]=1)(=[O:3])[CH3:2].[C:12]1([CH2:18][S:19][CH:20]([C:24](O)=[O:25])[C:21](O)=[O:22])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:10][C:8]1[CH:9]=[C:4]([C:1]2[O:3][C:21](=[O:22])[C:20]([S:19][CH2:18][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[C:24]([OH:25])[CH:2]=2)[CH:5]=[C:6]([CH3:11])[N:7]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared from the condensation of the trimethylsilyl enol ether of 4-acetyl-2,6-dimethylpyridine and the diethyl ester of [(phenylmethyl)thio]propanedioic acid following the same procedure outlined in Method A; m.p. 88°-90° C. NMR (DMSO-d6) δ 2.55 (s, 6 H), 4.02 (s, 2 H), 6.85 (s, 1 H), 7.16-7.28 (m, 5 H), 7.40 (s, 2 H).
Quellen und Nachweise
- ORD-Eintrag
- ord-4a8c03512df344239845230c9210e842
- Quelldatensatz
- uspto-grants-1998_09