4-(3-(2-Benzyloxyphenyl)propyl]benzoic acid → 4-[2-(2-Benzyloxyphenyl)-(Z)-ethenyl]-2-methoxybenzoic acid

Beteiligte Stoffe

Reaktionsschritte

Methyl 4-[2-(2-benzyloxyphenyl)-(Z)-ethenyl]-2-methoxy-benzoate (obtained from methyl 4-[2-(2-benzyloxyphenyl)-(Z)-ethenyl]-2-hydroxybenzoate as described in Example 14) was converted to 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoic acid (containing 15% of the (Z) isomer and obtained as a gum; negative FAB mass peak 359) using the method described in Example 1 for the conversion of methyl 4-[3-(2-benzyloxyphenyl)propyl]benzoate to 4-[3-(2-benzyloxyphenyl)-propyl]benzoic acid.

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