2-Amino-4-chlorobenzoic acid → HCID 18971523, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([N:12]=[C:13]=[O:14])(=[O:11])=[O:10])=[CH:5][CH:4]=1.[NH2:15][C:16]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:17]=1[C:18]([OH:20])=O>>[Cl:25][C:23]1[CH:24]=[C:16]2[C:17]([C:18](=[O:20])[N:12]([S:9]([C:6]3[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)(=[O:11])=[O:10])[C:13](=[O:14])[NH:15]2)=[CH:21][CH:22]=1Komponenten
3
Versuchsvorschrift
1.14 g (5.35 mmol) of 4-methoxybenzenesulfonylisocyanate and 938 mg (5.35 mmol) of 2-amino-4-chlorobenzoic acid were treated in the same way as in Example 1 to obtain 938 mg of the above-identified compound (yield 64.3%). Properties: colorless crystal, Melting point: >200° C. (decomposition), PMR (δppm, DMSO-d6):3.88 (3H,s), 7.12 (1H,s), 7.17-7.23 (3H,m), 7.85 (1H,d), 8.10 (2H,d), 11.68 (1H,br).
Quellen und Nachweise
- ORD-Eintrag
- ord-8ad0893041834149982ba672b03a6756
- Quelldatensatz
- uspto-grants-1998_09
- DOI