HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Rolipram → 1-(6-Fluoroquinolin-2-ylmethyl)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Rolipram | HCID 5092 | — |
| Edukt | 2-(Chloromethyl)-6-fluoroquinoline | HCID 11241007 | — |
| Produkt | 1-(6-Fluoroquinolin-2-ylmethyl)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone | HCID 18971748 | — |
Reaktionsschritte
Reaction of 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone with 2-chloromethyl-6-fluoroquinoline, analogous to the procedure of Example 29, yielded the title compound. M.P.: 65°-68° C. High Resolution Mass Spectra: Calc'd: 434.1983. Found: 434.2005.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05814651 |
| Quelldatensatz | uspto-grants-1998_09 |
| ORD ID | ord-dcc912890d2a40a783f98d42569334ef |
| Quellennotiz | uspto-grants-1998_09 |