Potassium Hydroxide → 6-(dimethylamino)-1H-indole-2-carboxylic acid

HRID 2395773Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2395773
[CH3:1][N:2]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[C:9]([C:13]([O:15]C)=[O:14])[NH:10]2)=[CH:6][CH:5]=1)[CH3:3].[OH-].[K+]>>[CH3:3][N:2]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[C:9]([C:13]([OH:15])=[O:14])[NH:10]2)=[CH:6][CH:5]=1)[CH3:1]

Komponenten

3

Edukt 2

HCID 14797Potassium HydroxideHCID 4715276methyl 6-(dimethylamino)-1H-indole-2-carboxylate

Produkt 1

HCID 51599086-(dimethylamino)-1H-indole-2-carboxylic acid

Versuchsvorschrift

Following the general procedure of PREPARATION 63 and making non-critical variations but starting with methyl 6-(N,N-dimethylamino)indole-2-carboxylate (PREPARATION 88, 0.80 g), potassium hydroxide (0.25 g), the title compound is obtained, NMR (300 MHz, CD3OD) 7.62, 7.13, 7.11, 7.01, and 3.11 δ.

Aufarbeitung

  1. customthe general procedure of PREPARATION 63

Quellen und Nachweise

ORD-Eintrag
ord-2a2183cb021549fb8816cb1dc407b928
Quelldatensatz
uspto-grants-1996_02
Patentnummer
US05489593

Notizen zur Reaktion

Wird geladen…