[Na].[SH:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:6]=[N:5][N:4]=1.Cl[CH2:15][N:16]1[C:20](=[O:21])[CH:19]([CH2:22][CH2:23][CH3:24])[NH:18][S:17]1(=[O:26])=[O:25]>CN(C=O)C>[C:8]1([N:7]2[C:3]([S:2][CH2:15][N:16]3[C:20](=[O:21])[CH:19]([CH2:22][CH2:23][CH3:24])[NH:18][S:17]3(=[O:25])=[O:26])=[N:4][N:5]=[N:6]2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1The sodium salt of 5-mercapto-l-phenyl-1H-tetrazole (0.42 g) ##STR16## was added to a solution of 2-chloromethyl-4-propyl-1,2,5-thiadiazolidin-3-one 1, 1-dioxide (0.44 g) in DMF (10 ml), and the resulting mixture was allowed to react at 50° C. for 6 hours and then cooled. The mixture was poured into ice/water, extracted with ethyl acetate, and the organic layer was washed with water and brine, dried, and concentrated in vacuo. The residue was purified by flash chromatography (35% ethyl acetate in hexane) to afford 0.69 g (96%) of 2-(1-phenyl-1H-tetrazol-5-yl-thiomethyl)-4-propyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide (Formula I: R1 =H; R2 =propyl;
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