Sulfuric Acid → 1-Ethyl-4-(4-fluorophenyl)benzene

HRID 2398317Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2398317
C(C1C=CC(C2C=CC=CC=2F)=CC=1)#C.[C:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)#[CH:17].S(=O)(=O)(O)O.[H][H]>>[CH2:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)[CH3:17]

Komponenten

5

Edukt 4

HCID 1118Sulfuric AcidHCID 42040FluretofeneHCID 196905164-Ethynyl-4'-fluoro-1,1'-biphenylHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 214329111-Ethyl-4-(4-fluorophenyl)benzene

Versuchsvorschrift

The procedure of Example 1 was repeated, except that the 1-ethynyl-4-(2-fluorophenyl)benzene was replaced with 1.5 g. of 1-ethynyl-4-(4-fluorophenyl)benzene, the amount of catalyst was reduced to 0.5 g., the sulfuric acid was omitted, initial hydrogen pressure was 48 psig., and the reduction was allowed to proceed overnight. Evaporation of the benzene left a solid which was recrystallized from hexane to give 1-ethyl-4-(4-fluorophenyl)benzene, mp 60° -63°. The following elemental analysis was obtained:

Aufarbeitung

  1. customEvaporation of the benzene
  2. waitleft a solid which
  3. customwas recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-bd19399e534b4269b6b553f2ea47117e
Quelldatensatz
uspto-grants-1977_05
Patentnummer
US04024284

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