Methyl N-cyanocarbamate → 5-Cyclohexylethylthio-2-carbomethoxyaminobenzimidazole
Reaktionsgleichung
[N+:1]([C:4]1[CH:10]=[CH:9][C:8]([S:11][CH2:12][CH2:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)=[CH:7][C:5]=1[NH2:6])([O-])=O.[C:20]([NH:24][C:25]#N)([O:22][CH3:23])=[O:21]>>[CH:14]1([CH2:13][CH2:12][S:11][C:8]2[CH:9]=[CH:10][C:4]3[N:1]=[C:25]([NH:24][C:20]([O:22][CH3:23])=[O:21])[NH:6][C:5]=3[CH:7]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1Komponenten
3
Versuchsvorschrift
Repeating the reaction of Example 1 but using 10.0 g. of cyclohexylethylthiol gives 2-nitro-5-cyclohexylethylthioaniline. The nitro compound is reduced. The reduction mixture is reacted with carbomethoxycyanamide as described to give 5-cyclohexylethylthio-2-carbomethoxyaminobenzimidazole.
Quellen und Nachweise
- ORD-Eintrag
- ord-daa640345104442a88f6a1a9fd58de27
- Quelldatensatz
- uspto-grants-1977_05