Hydrochloric Acid → 4-Ethylaminomethyl-4-hydroxypiperidine dihydrochloride

HRID 2400077Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2400077
[CH2:1]([NH:3][CH2:4][C:5]1([OH:16])[CH2:10][CH2:9][N:8](C(OCC)=O)[CH2:7][CH2:6]1)[CH3:2].[ClH:17]>>[ClH:17].[ClH:17].[CH2:1]([NH:3][CH2:4][C:5]1([OH:16])[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1)[CH3:2]

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 19382186HCID 19382186, Verbindung

Produkt 1

HCID 193821764-Ethylaminomethyl-4-hydroxypiperidine dihydrochloride

Versuchsvorschrift

4.6 g (20 mmol) of ethyl 4-ethylaminomethyl-4-hydroxypiperidine-1-carboxylate are heated overnight under reflux with 35 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are triturated with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.

Aufarbeitung

  1. concentrationThe product is concentrated
  2. customthe crystals are triturated with acetone
  3. filtrationfiltered off with suction
  4. dry with materialdried in a vacuum desiccator over P4O10

Quellen und Nachweise

ORD-Eintrag
ord-c0d7121fd6074758bc75edd21881b338
Quelldatensatz
uspto-grants-1995_09
Patentnummer
US05453422

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