Isopropyl iodide → 6-Amino-2-(butyloxy)-9-{[1-(1-methylethyl)-4-piperidinyl]methyl}-7,9-dihydro-8H-purin-8-one
Reaktionsgleichung
[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:22]C)[N:12]2[CH2:15][CH:16]2[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]2)=[C:8]([NH2:24])[N:7]=1)[CH2:2][CH2:3][CH3:4].I[CH:26]([CH3:28])[CH3:27]>>[NH2:24][C:8]1[N:7]=[C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[N:14]=[C:13]2[C:9]=1[NH:10][C:11](=[O:22])[N:12]2[CH2:15][CH:16]1[CH2:21][CH2:20][N:19]([CH:26]([CH3:28])[CH3:27])[CH2:18][CH2:17]1Komponenten
3
Versuchsvorschrift
Prepared similarly to Example 24 from 2-(butyloxy)-8-(methyloxy)-9-(4-piperidinylmethyl)-9H-purin-6-amine and 2-iodopropane.
Quellen und Nachweise
- ORD-Eintrag
- ord-cce6d54ecca842b094b005e2adc1f62c
- Quelldatensatz
- uspto-grants-2014_08