HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,1-Dimethylethyl (3aS,6aS)-hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate → (3aS,6aS)-tert-butyl 5-(5-(3,5-difluorophenylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[2,3-c]pyrrole-1(2H)-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,1-Dimethylethyl (3aS,6aS)-hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 29949089 | — |
| Edukt | 5-bromo-N-(3,5-difluorophenyl)nicotinamide | HCID 41601149 | — |
| Produkt | (3aS,6aS)-tert-butyl 5-(5-(3,5-difluorophenylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[2,3-c]pyrrole-1(2H)-carboxylate | HCID 67265843 | — |
Reaktionsschritte
The product from Example 53A and (3aS,6aS)-tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate (prepared as described in WO2001081347) were processed as described in Example 53B to provide the title compound. MS (APCI) m/z=445 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08648084B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-675ac849444c474f85b701a72f53dd1d |
| Quellennotiz | uspto-grants-2014_02 |