2-Amino-5-nitrobenzoic acid → HCID 178526470, Verbindung

HRID 240566

Reaktionsgleichung

Reaktionsgleichung von HRID 240566
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.C(O)(=O)C.[CH:18](N)=[NH:19]>COC(O)C>[N+:11]([C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[CH:18][N:19]=[C:4]2[OH:6])([O-:13])=[O:12]

Komponenten

4

Edukt 2

HCID 120322-Amino-5-nitrobenzoic acidHCID 160693Formamidine acetate

Produkt 1

HCID 178526470HCID 178526470, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 30156371-MethoxyethanolLösungsmittel

Reaktionsbedingungen

Temperatur
115 °C

Versuchsvorschrift

A mixture of 2-amino-5-nitrobenzoic acid (1000 g, 5 mol) and formamidine acetate (1000 g, 10 mol) were dissolved in methoxyethanol (4 L) and heated to 115° C. for 16 hours. After cooling the mixture to room temperature, ice water (5 L) was added and the mixture was stirred for 30 minutes before collecting the product (125 g, 14%) by filtration.

Aufarbeitung

  1. temperatureAfter cooling the mixture to room temperature
  2. custombefore collecting the product (125 g, 14%)
  3. filtrationby filtration

Quellen und Nachweise

ORD-Eintrag
ord-c6eaa425e0df4e24ab878d970d8aa4c3
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08648087B2

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