HCID 58413223, Verbindung → HCID 58413003, Verbindung

HRID 240599Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 240599
[F:1][C:2]1[CH:3]=[CH:4][C:5]([N+:14]([O-])=O)=[C:6]([CH:13]=1)[O:7][C@@H:8]1[CH2:12][CH2:11][O:10][CH2:9]1>CO.[Ni]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:14])=[C:6]([O:7][C@@H:8]2[CH2:12][CH2:11][O:10][CH2:9]2)[CH:13]=1

Komponenten

4

Edukt 1

HCID 58413223HCID 58413223, Verbindung

Produkt 1

HCID 58413003HCID 58413003, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of (R)-3-(5-fluoro-2-nitrophenoxy)tetrahydrofuran (1.8 g) in MeOH (60.0 ml) was added Ra/Ni (200.0 mg), the mixture hydrogenated at room temperature. The catalyst was filtered off and the filtrate was concentrated.

Aufarbeitung

  1. customhydrogenated at room temperature
  2. filtrationThe catalyst was filtered off
  3. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-e3a4a21eea60440e913ef549c8f7f5e3
Quelldatensatz
uspto-grants-2014_02
Patentnummer
US08648068B2

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