HCID 178518552, Verbindung → HCID 178517909, Verbindung
Reaktionsgleichung
S[C:2]1[N:3]=[C:4]([OH:14])[C:5]2[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][C:6]=2[N:7]=1>[Ni].CCO>[N:7]1[C:6]2[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:5]=2[C:4]([OH:14])=[N:3][CH:2]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A mixture of 2-mercapto-5,6,7,8,9,10-hexahydrocycloocta[d]-pyrimidine-4-ol (1 g; 4.76 mmol) and 10 g of Raney nickel in 40 mL of abs. EtOH was refluxed for 5 hours and filtered. The filtrate was evaporated to give 5,6,7,8,9,10-hexahydrocycloocta[d]-pyrimidine-4-ol as a pale-grey solid (0.66 g; 78% yield).
Aufarbeitung
- filtrationfiltered
- customThe filtrate was evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-4a9d5310162a4213980cb3b9ab889511
- Quelldatensatz
- uspto-grants-2014_08
- Patentnummer
- US08809347B2
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