HCID 66821881, Verbindung → 1-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl)butan-1-amine

HRID 2406578Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2406578
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])=[CH:9][CH:8]=1)[CH3:2].N1(CCOC2C=CC(C(=O)CCC)=CC=2)CCCC1>>[N:3]1([CH2:4][CH2:5][O:6][C:7]2[CH:8]=[CH:9][C:10]([CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])=[CH:11][CH:12]=2)[CH2:1][CH2:2][CH2:19][CH2:18]1

Komponenten

3

Edukt 2

HCID 66821881HCID 66821881, VerbindungHCID 66822143HCID 66822143, Verbindung

Produkt 1

HCID 668224831-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl)butan-1-amineAusbeute 45 %

Versuchsvorschrift

The title compound was prepared by using a similar procedure as described for the preparation of 25 except that 1-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butan-1-one (23) was used instead of 1-(4-(2-(diethylamino)ethoxy)phenyl)butan-1-one (21). This produced crude 27 (188 mg, 45%) as a yellow oil: MS (ES+) m/z 263.2 (M+H)+.

Aufarbeitung

  1. customThe title compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-db6f95e9da85410e9bb99e467030d449
Quelldatensatz
uspto-grants-2014_08
Patentnummer
US08809377B2

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